Introduction: Leptospirosis is a bacterial infection caused by Leptospira spirochetes.This zoonotic disease is primarily transmitted to humans through contact with contaminated water or soil, often from the urine of infected animals.While it is more common in tropical regions, the incidence of leptospirosis has increased globally, particularly foll
Impact of COVID-19 and other pandemics and epidemics on people with pre-existing mental disorders: a systematic review protocol and suggestions for clinical care
Introduction The current COVID-19 pandemic has resulted in high rates of infection and death, as well as widespread social disruption and a reduction in access to healthcare services and support.There is growing concern over how the pandemic, as well as measures put in place to curb the pandemic, will impact people with mental disorders.We aim to C
Early leucine programming on protein utilization and mTOR signaling by DNA methylation in zebrafish (Danio rerio)
Abstract Background Early nutritional programming affects a series of metabolism, growth and development in mammals.Fish also exhibit the developmental plasticity by early nutritional programming.However, little is known about the effect of early amino acid programming on growth and metabolism.Methods In the present study, zebrafish (Danio rerio) w
The Association of H. pylori infection and patterns of erythematous gastric mucosa
It has been uncertain what types of erythematous gastric mucosa are produced by Helicobacter pylori (H.pylori)-infection.We therefore design the present study to identify the type of erythematous mucosa associated with H.pylori-infection.A total of 590 consecutive Japanese patients (mean age 58.7 years, 185 men and 405 women) referred to our hospit